American Veterinarian Medical Association

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The statement in the story “Pain relief needed in youngest pigs” (JAVMA, May 1, 2015) that “residues from drugs without established tolerance levels would be illegal, and the Food and Drug Administration would need to establish residue tolerance levels for veterinarians to determine what withdrawal times are needed” requires clarification. In fact, the FDA is unlikely to establish residue tolerance concentrations unless a drug sponsor provides relevant pharmacokinetic data. In the absence of established tolerance levels, veterinarians can still estimate withdrawal times but must do so on the basis of limited data or by extrapolation beyond currently available data.