Monographs available for dewormers, anticonvulsant

Published on December 15, 2005
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Monographs on a category of dewormers and an anticonvulsant are now available online from the U.S. Pharmacopeia's Veterinary Medicine Information Expert Committee.

The monograph on tetrahydropyrimidines, a category of dewormers, includes information on morantel and pyrantel. This type of anthelmintic drug is effective in the prevention or treatment of gastrointestinal nematodes in pigs, cats, cattle, dogs, goats, and horses and ponies.

The monograph on bromide, an anticonvulsant, notes that commercial bromide products are not available in the United States or Canada. Bromide is used in the treatment of epilepsy in dogs.

Practitioners must purchase bromide as medicinal- or analytic-grade potassium or sodium bromide from an approved source and compound for veterinary use. Practitioners can refer to the Animal Medicinal Drug Use Clarification Act and Food and Drug Administration regulations pertaining to compounding, as well as the current FDA Compliance Policy Guide on "Compounding of drugs for use in animals."

The USP has also published veterinary monographs on antimicrobial and anti-inflammatory drugs. Each monograph includes sections about indications for use, regulatory considerations, chemistry, pharmacology/pharmacokinetics, precautions to consider, possible adverse effects, veterinary dosing, overdosing, and client consultation.

Monographs are available here.