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AVMA - Animal Medicinal Drug Use Clarification Act (AMDUCA)
Extralabel drug use algorithm
a drug labeled for food animals exist which fulfills all of the following?...
there a drug approved for animals which could be used extralabelly?
there a human drug or drug approved for non-food animals which could be used extralabelly?
If compounding of approved drugs will prevent animal pain and suffering, refer to FDA Compliance Policy Guide for compounding guidance.
***Compounding of bulk drugs is illegal
†Drugs Prohibited for Extralabel Use in Food Animals (Current as of April 2012. Check for updates on the FDA Web site at
Furazolidone, Nitrofurazone, other Nitrofurans
Glycopeptides (ex: vancomycin)
Sulfonamide drugs in lactating dairy cows (except approved use of sulfadimethoxine, sulfabromomethazine, and sulfaethoxypyridazine).
Phenybutazone in female dairy cattle 20 months of age or older.
Adamantane and neuraminidase inhibitor classes of drugs that are approved for treating or preventing influenza A are prohibited therapy in chickens, turkeys, and ducks.
Cephalosporin (excluding cephapirin) in cattle, swine, chickens, or turkeys
Using cephalosporin drugs at unapproved dose levels, frequencies, durations or routes of administration is prohibited;
Using cephalosporin drugs in cattle, swine, chickens, or turnkeys that are not approved for use in that species (e.g., cephalosporin drugs intended for humans or companion animals);
Using cephalosporin drugs for disease prevention.
OTHER AVMA SITES
Externs on the Hill
National Pet Week
Animal Health SmartBrief
WebMD® Pet Health Community
American Veterinary Medical Association