The responsible use of animals for human purposes, such as companionship, food, fiber, recreation, work, education, exhibition, and research conducted for the benefit of both humans and animals, is consistent with the Veterinarian’s Oath.
"Being admitted to the profession of veterinary medicine, I solemnly swear to use my scientific knowledge and skills for the benefit of society through the protection of animal health and welfare, the prevention and relief of animal suffering, the conservation of animal resources, the promotion of public health, and the advancement of medical knowledge…"
The AVMA recognizes that animals have an important role in research, testing, and education for continued improvement of human and animal health and welfare. The AVMA also recognizes that humane care of animals used in research, testing, and education is an integral part of those activities.
Studying a virus' ability to promote tumor growth in mouse models
Glioblastoma is a aggressive form of malignant cancer and researchers, with the help of mouse models, are studying the effect of cytomegalvirus (CVM) on the growth of this type of brain cancer. Through use of these animal models, we can improve understanding of cancer mechanisms and find better ways to treat cancer in the future.
Link to full article: http://journal.frontiersin.org/article/10.3389/fonc.2015.00061/abstract
Recent technological advances in using mouse models to study ovarian cancer
Serous epithelial ovarian cancer (SEOC) is the most lethal gynecological cancer in the United States with disease recurrence being the major cause of morbidity and mortality. Despite recent advances in our understanding of the molecular mechanisms responsible for the development of SEOC, the survival rate for women with this disease has remained relatively unchanged in the last two decades. Preclinical mouse models of ovarian cancer, including xenograft, syngeneic, and genetically engineered mice, have been developed to provide a mechanism for studying the development and progression of SEOC. Such models strive to increase our understanding of the etiology and dissemination of ovarian cancer in order to overcome barriers for early detection and resistance to standard chemotherapy.Link to full article: http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00026/full
Link to full article: http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00026/full