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Vaccine-Associated Feline Sarcoma Task Force


VAFSTF Selected Bibliographic References

Alsarraf R. Update on feline vaccine-associated fibrosarcomas. Vet Med Us 1998;93:729.

Banerji N, Li X, Klausner JS, et al. Evaluation of in vitro chemosensitivity of vaccine-associated feline sarcoma cell lines to vincristine and paclitaxel. Am J Vet Res 2002;63:728-732.

Barber LG, Sorenmo KU, Cronin KL, et al. Effect of combined doxorubicin and cyclophosphamide therapy on non-resectable feline fibrosarcoma. Proceedings VCS 16th Annual Conference. 1996;53. Ref Type:Conference Proceeding

Barber LG, Sorenmo KU, Cronin KL, Shofer FS. Combined doxorubicin and cyclophosphamide chemotherapy for nonresectable feline fibrosarcoma. J Amer.Anim Hosp.Assn. 2000;36:416-421.

Bailey DB, Rassnick KM, Erb HN, et al. Effect of glomerular filtration rate on clearance and myelotoxicity of carboplatin in cats with tumors. Am J Vet Res 2004;65:1502-1507. 1998;213:1424-1425.

Bellinger DA, Chang J, Bunn TO, et al. Rabies induced in a cat by high-egg-passage Flury strain vaccine. J Am Vet Med Assoc 1983;183:997-998.

Bergman P, Hendrick MJ, Macy D, Mcgill LD, Starr RM, Van Kampen KR. Feline Sarcoma and Vaccination. Veterinary Forum March 1999;40-47.

Bergman PJ. Etiology of feline vaccine-associated sarcomas: history and update. J Amer.Vet Med.Assn. 1998;213:1424-1425.

Bongiovani S, Bengston AE, Gliatto JM. Prognostic indicators associated with adjuvant radiotherapy for cats with soft tissue sarcoma. Proceedings Veterinary Cancer Society 19th Annual Conference. 1999;44. Ref Type:Conference Proceeding.

Borjesson D, Madewell BR, McEntee MC, et al. Feline vaccine-associated fibrosarcomas. Vet Cancer Soc Newsl 1999;23:1-11.

Brand KG, Johnson KH, Buoen LC. Foreign body tumorigenesis. CRC Crit Rev Toxicol 1976;4:353-394.

Brearley MJ. Vaccine-associated feline sarcomas. Vet Rec. 2001;148:580.

Bregazzi VS, LaRue SM, McNiel E, Macy DW, Dernell WS, Powers BE, Withrow SJ. Treatment with a combination of doxorubicin, surgery, and radiation versus surgery and radiation alone for cats with vaccine-associated sarcomas: 25 cases (1995-2000). J Amer.Vet.Med.Assn. 2001;218:547-550.

Burke JK, Sorenmo K, Duda L, Shofer F. The effect of adjuvant orthovoltage radiation therapy on feline vaccine-associated fibrosarcomas: a retrospective study of 15 cases. Proceedings VCS 19th Annual Conference. 1999;20. Ref Type:Conference Proceeding

Burton G, Mason KV. Do postvaccinal sarcomas occur in Australian cats? Aust.Vet.J. 1997;75:102-106.

Carew JS, Schmidt JA, Humphrey SA, et al. Growth factor expression and vaccine-associated sarcoma tumorigenicity, in Proceedings. 19th Annu Vet Cancer Soc Conf 1999;11-13.

Carroll EE, Dubielzig RR, Schultz RD. Cats differ from mink and ferrets in their response to commercial vaccines: A histologic comparison of early vaccine reactions. Vet.Pathol. 2002;39:216-227.

Cohen M, Wright JC, Brawner WR, Smith AN, Henderson R, Behrend EN. Use of surgery and electron beam irradiation, with or without chemotherapy, for treatment of vaccine-associated sarcomas in cats: 78 cases (1996-2000). J Amer.Vet. Med. Assn. 2001;219:1582-1589.

Couto CG, Griffey SM, Naydan DK, Madewell BR. Feline vaccine-associated sarcomas: a morphological study and immune phenotyping of intratumoral and peritumoral leukocyte population. Proceedings VCS 19th Annual Conference. 1999;34.Ref Type:Conference Proceeding.

Couto CG, Macy DW. Review of treatment options for vaccine-associated feline sarcoma. J.Amer.Vet.Med.Assn. 1998;213:1426-1427.

Couto SS, Griffey SM, Duarte PC, Madewell BR. Feline vaccine-associated fibrosarcoma: Morphologic distinctions. Vet Pathol. 2002;39:33-41.

Coyne MJ, Reeves NCP, Rosen DK. Estimated prevalence of injection-site sarcomas in cats during 1992. J Am Vet Med Assoc 1997;210:249-251.

Cronin K, Page RL, Spodnick G, Dodge R, Hardie EN, Price GS, Ruslander D, Thrall DE. Radiation-Therapy and Surgery for Fibrosarcoma in 33 Cats. Vet.Radiol.Ultrasound. 1998;39:51-56.

Dambach D, Carlson J, Riddle D, Hendrick M. Immunohistochemical identification and localization of growth factors in feline postvaccinal lesions (abstr). Vet Pathol. 1996;33:607. Ref Type:Abstract.

Davidson EB, Gregory CR, Kass PH, et al. Results of surgical excision of soft tissue fibrosarcomas in cats. Proceedings VCS 16th Annual Conference. 1996;58. Ref Type:Conference Proceeding

Davidson EB, Gregory CR, Kass PH. Surgical excision of soft tissue fibrosarcomas in cats. Vet Surg 1997;26:265-269.

Doddy FD, Glickman LT, Glickman NW, et al. Feline fibrosarcomas at vaccination sites and non-vaccination sites. J Comp Pathol 1996;114:165-174.

Dubielzig, RR, Hawkins, KL, and Miller, PE. Myofibroblastic Sarcoma Originating at the Site of Rabies Vaccination in a Cat. J.Vet.Diagn.Invest. 1993;5:637-638.

Ehrhart N, Helfand S, Kitchell B, LaRue S. The "best" way to treat vaccine-associated sarcomas - issues for multimodality therapy. ACVIM Veterinary Medical Forum. 2001;19: 503-504. Ref Type:Conference Proceeding.

Ellis, JA, Jackson, ML, Bartsch, RC, Mcgill, LG, Martin, KM, Trask, R, and Haines, DM. Use of Immunohistochemistry and Polymerase Chain-Reaction for Detection of Oncornaviruses in Formalin-Fixed, Paraffin-Embedded Fibrosarcomas from Cats. J.Amer.Vet.Med.Assn. 1996;209:767-767.

Erlewein DL. Post-vaccinal rabies in a cat. Feline Pract 1981;11(2):16-21.

Esh JB, Cunningham JG, Wiktor TJ. Vaccine-induced rabies in four cats. J Am Vet Med Assoc 1982;180:1336-1339.

Esplin DG. Widespread metastastisis of a fibrosarcoma associated with a vaccination site in a cat. Feline Pract 1995;23(1):13-16.

Esplin DG. Metastasizing liposarcoma associated with a vaccination site in a cat. Feline Pract 1996;24(5):20-23.

Esplin DG, Mcgill LD. Fibrosarcoma at the site of lufenuron injection in a cat. Vet Cancer Soc Newsl 1999;23:8-9.

Esplin DG, Mcgill LD, Meininger AC, et al. Postvaccination sarcomas in cats. J Am Vet Med Assoc 1993;202:1245-1247.

Ettinger SN, Hohenhaus AE, Bergman PJ. Preliminary comparison of tumor response to trimodality therapy with or without adjuvant hemoglobin-based oxygen carrier for feline vaccine associated soft tissue sarcomas. Veterinary Cancer Society. 2001. Ref Type: Conference Proceeding.

Gagnon AC. Drug injection-associated fibrosarcoma in a cat. Feline Pract. 2000;28:18.

Gobar GM, Kass PH. World Wide Web-based survey of vaccination practices, postvaccinal reactions, and vaccine site-associated sarcomas in cats. J. Amer.Vet Med.Assn. 2002;220:1477-1482.

Gustafson NR, LaRue SM, Komurek K, et al. Radiation sensitivity of feline fibroblasts: are cats more radiation resistant than dogs? Proceedings VCS 18th Annual Conference. 1999;49. Ref Type:Conference Proceeding

Hendrick MJ, Bergman PJ, Couto CG, et al. Vaccine-associated feline sarcoma symposium. J Am Vet Med Assoc 1998;213:1422-1430.

Hendrick, M, Goldschmidt, MH. Do injection site reactions induce fibrosarcomas in cats? J.Amer.Vet.Med.Assn. 1991;199:968.

Hendrick MJ. Feline vaccine-associated sarcomas, Cancer Invest. 1999;17:273-277

Hendrick MJ. Historical review and current knowledge of risk factors involved in feline vaccine-associated sarcomas, J.Amer.Vet Med.Assn. 1998;213:1422-1423

Hendrick MJ. Feline vaccine-associated sarcomas: current studies on pathogenesis, J.Amer.Vet Med.Assn. 1998;213:1425-1426

Hendrick, MJ, Brooks, JJ. Postvaccinal Sarcomas in the Cat - Histology and Immunohistochemistry. Vet Pathol. 1994;31:126-129.

Hendrick, MJ, Goldschmidt, MH, Shofer, FS, Wang, YY, and Somlyo, AP. Postvaccinal sarcomas in the cat: epidemiology and electron probe microanalytical identification of aluminum. Cancer Res. 1992;52:5391-5394.

Hendrick, MJ, Kass, PH, Mcgill, LD, and Tizard, IR. Postvaccinal Sarcomas in Cats. J.Nat.Cancer Inst. 1994;86:341-343.

Hendrick, MJ, Shofer, FS, Goldschmidt, MH, Haviland, JC, Schelling, SH, Engler, SJ, and Gliatto, JM(1994). Comparison of Fibrosarcomas That Developed at Vaccination Sites and at Nonvaccination Sites in Cats - 239 Cases (1991-1992). J.Amer.Vet.Med.Assn. 1994;205:1425-1429.

Hennings H, Devor D, Wenk ML, et al. Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethybenz(a)-anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice: effects of tumor promoters and steriodal anti-inflammatory agents on skin of newborn mice in vivo and in vitro. Cancer Res 1981;41:773-779.

Hershey AE, Dubielzig RR, Helfand SC. Overexpression of p53 in feline vaccine-associated sarcomas. 32-32. 1999. Proceedings VCS 19th Annual Conference. 1999;32. Ref Type:Conference Proceeding

Hershey AE, Sorenmo K, Hendrick MJ, Shofer F. Feline fibrosarcoma: prognosis following surgical treatment: a preliminary report. Proceedings VCS 17th Annual Conference. 1997;36. Ref Type: Conference Proceeding

Hershey AE, Sorenmo KU, Hendrick MJ, Shofer FS, Vail DM. Prognosis for presumed feline vaccine-associated sarcoma after excision: 61 cases (1986-1996), J Amer.Vet Med Assn. 2000;216:58-61

Hershey E, Sorenmo K, Hendrick M, Schofer F, Vail D. Feline vaccine-associated fibrosarcomas: Prognosis following surgical excision: a retrospective analysis of 61 cases. Veterinary Surgery. 1999;28[5]:394. Ref Type:Abstract.

Hill AB. The environment and disease: association or causation, in Proceedings. Royal Soc Med 1965;58:295-300.

Hoots EA, McNeil EA, LaRue SM. Characterization of genetic alterations in feline vaccine-associated sarcoma using whole chromosome painting probes (abstr). American College of Veterinary Internal Medicine. 2001;21:83. Ref Type:Conference Proceeding.

Jeglum KA, deGuzman E, Young KM. Chemotherapy of advanced mammary adenocarcinoma in 14 cats. J Am Vet Med Assoc 1985;187:157-160.

Jelínek F. Postinflammatory sarcoma in cats. Exp Toxicol Pathol 2003;55:167-172.

Jones PD, Kitchell BE. Vaccine-associated sarcomas in cats: Applying the latest research to practice. Vet Med US. 2002;97:34.

Kanjilal S, Banerji N, Fifer A, et al. p53 Tumor suppressor gene alterations in vaccine-associated feline sarcoma. Proceedings VCS 19th Annual Conference. 1999;48. Ref Type:Conference Proceeding

Kass PH, Barnes WG, Spangler WL, et al. Epidemiologic evidence for a causal relation between vaccination and fibrosarcoma tumorigenesis in cats. J Am Vet Med Assoc 1993;203:396-405.

Kass PH, Spangler WL, Hendrick MJ, et al. Multicenter case-control study of risk factors associated with development of vaccine-associated sarcomas in cats. J Am Vet Med Assoc 2003;223:1283-1292.

Katayama R, Huelsmeyer MK, Marr AK, et al. Imatinib mesylate inhibits platelet-derived growth factor activity and increases chemosensitivity in feline vaccine-associated sarcoma. Cancer Chemother Pharmacol 2004;54:25-33.

Kidney BA, Ellis JA, Haines DM, Jackson ML. Comparison of endogenous feline leukemia virus RNA content in feline vaccine and nonvaccine site-associated sarcomas. Amer.J Vet Res. 2001;62:1990-1994.

Kidney BA, Ellis JA, Haines DM, Jackson ML. Evaluation of formalin-fixed paraffin-embedded tissues obtained from vaccine site-associated sarcomas of cats for DNA of feline immunodeficiency virus. Amer.J Vet Res. 2000;61:1037-1041.

Kidney BA, Haines DM, Ellis JA, Burnham ML, Jackson ML. Evaluation of formalin-fixed paraffin-embedded tissues from feline vaccine site-associated sarcomas for feline foamy virus DNA. Amer.J Vet Res. 2002;63:60-63.

Kidney BA, Haines DM, Ellis JA, Burnham ML, Jackson ML. Evaluation of formalin-fixed paraffin-embedded tissues from vaccine site-associated sarcomas of cats for polyomavirus DNA and antigen. Amer.J Vet Res. 2001;62:828-832.

Kidney BA, Haines DM, Ellis JA, Burnham ML, Teifke JP, Czerwinski G, Jackson ML. Evaluation of formalin-fixed paraffin-embedded tissues from vaccine site-associated sarcomas of cats for papillomavirus DNA and antigen. Amer.J Vet Res. 2001;62:833-839.

King GK, Harris DF, Hottinger H, Freeman KP, Hahn KA. Prolonged remission and survival time in cats with injection-site sarcomas using pre-operative radiation and doxorubicin protocol: 61 cases (1998-2000). American College of Veterinary Radiology. 2001. Ref Type:Conference Proceeding.

Kobayashi T, Hauck ML, Dodge R, et al. Preoperative radiotherapy for vaccine associated sarcoma in 92 cats. Vet Radiol Ultrasound 2002;43:473-479.

Kobayashi T, Hauck ML, Price GS. A retrospective analysis of 189 cats evaluated for feline vaccine site sarcoma from 1985 to 1998 (abstr). Veterinary Cancer Society. 1999;19:23. Ref Type:Conference Proceeding.

Kuntz CA. Modified wide local excision for vaccine associated soft tissue sarcomas in cats (abstr). Veterinary Surgery. 2000;29[5]:481. Ref Type:Abstract.

Kuntz CA. Sarcoma surgery technique debated [lett]. Veterinary Practice News 2001;13(11):5.

Lester S, Clemett T, Burt A. Vaccine site-associated sarcomas in cats: clinical experience and laboratory review (1982-1993). J Am Anim Hosp Assoc 1996;32:91-95.

Leveque NW. Update on vaccine-associated sarcoma. J.Amer.Vet.Med.Assn. 1998;212:1350.

Lidbetter DA, Williams FA, Krahwinkel DJ, Adams WH. Radical lateral body-wall resection for fibrosarcoma with reconstruction using polypropylene mesh and a caudal superficial epigastric axial pattern flap: A prospective clinical study of the technique and results in 6 cats. Vet Surger. 2002;31:57-64.

Macy DW. The Potential Role and Mechanisms of FeLV Vaccine-induced neoplasms. Semin.Vet.Med.Surg.Small.Anim. 1995;10:234-237.

Macy DW, Bergman, PJ. Vaccine-Associated Sarcomas in Cats. Feline.Pract. 1995;23:24-27.

Macy DW, Chretin J. Local postvaccinal reactions of a recombinant rabies vaccine. Veterinary Forum 1999;16:44-49.

Macy DW, Hendrick, MJ. The Potential Role of Inflammation in the Development of Postvaccinal Sarcomas in Cats. Vet.Clin.N.Amer.Small.Anim. 1996;26:103-103.

Macy DW. Vaccine adjuvants. Semin Vet Med Surg (Small Anim) 1997;12:206-211.

Madewell BR, Griffey SM, McEntee MC, Leppert VJ, Munn RJ. Feline vaccine associated fibrosarcoma: An ultrastructural study of 20 tumors (1996-1999). Vet Pathol. 2001;38:196-202.

Martins-Green M, Boudreau N, Bissell MJ. Inflammation is responsible for the development of wound-induced tumors in chickens infected with Rous sarcoma virus. Cancer Res 1994;54:4334-4341.

Massague J. The TGF-beta family of growth and differentiation factors. Cell 1987;49:437-438.

Matteucci ML, Anyarambhatla G, Rosner G, et al. Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas. Clin Cancer Res 2000;6:3748-3755.

Mcentee MC, Page RL. Feline vaccine-associated sarcomas. J Vet Intern.Med. 2001;15:176-182.

McEntee MC, Samii VF, Madewell BR. Contrast-enhanced computed tomography for treatment planning of feline vaccine-associated sarcomas: preliminary findings. Proceedings VCS 19th Annual Conference. 1999;62. Ref Type:Conference Proceeding

McEntee MC. Treatment decision making for cats with vaccine-associated sarcomas, Part 1 and II. In: Convention notes of the 138th Annual Convention of the American Veterinary Medical Association. Schaumburg, Ill: American Veterinary Medical Association, 2001;447-448.

McLeod DA, Thrall DE. The combination of surgery and radiation in the treatment of cancer: a review. Vet Surg 1989;18:1-6.

McNeil EA. Vaccine-associated sarcomas in cats - A unique cancer model. Clin Orthop.Related Res. 2001;21-27.

McNeil EA, Hoots EA, LaRue SM. Characterization of chromosomal aberrations in feline vaccine-associated sarcoma using comparative genomic hybridization (abstr). American College of Veterinary Internal Medicine. 2001;21:84. Ref Type:Conference Proceeding.

McNeil EA, LaRue SM, Vannais D, et al. Evaluation of feline rabies vaccines for mutagenicity using the AL assay. Proceedings VCS 18th Annual Conference. 1998;48. Ref Type:Conference Proceeding

Meyer EK. Vaccine-associated adverse events. Vet Clin N.Amer.Small Anim. 2001;31:493.

Meyer EK. Vaccine-associated feline sarcomas: a summary of USP data. Proceedings VCS 18th Annual Conference. 1998;47. Ref Type:Conference Proceeding

Morrison WB, Starr RM. Vaccine-associated feline sarcomas. J Am Vet Med Assoc 2001;218:697-702.

Munday JS, Stedman NL, Richey LJ. Histology and immunohistochemistry of seven ferret vaccination-site fibrosarcomas. Vet Pathol 2003;40:288-293.

Nambiar PR, Haines DM, Ellis JA, Kidney BA, Jackson ML. Mutational analysis of tumor suppressor gene p53 in feline vaccine site-associated sarcomas. Amer.J Vet Res. 2000;61:1277-1281.

Nambiar PR, Jackson ML, Ellis JA, Chelack BJ, Kidney BA, Haines DM. Immunohistochemical detection of tumor suppressor gene p53 protein in feline injection site-associated sarcomas. Vet Pathol. 2001;38:236-238.

Nieto A, Sánchez A, Martínez E, et al. Immunohistochemical expression of p53, fibroblast growth factor-β, and transforming growth factor-α in feline vaccine-associated sarcomas. Vet Pathol 2003;40:651-658.

Ogilvie G. Vaccine/injection associated sarcomas. Standards of Care: Emergency and Critical Care Medicine. 1999;1:5-10.

Ogilvie GK. Recent advances in the treatment of vaccine-associated sarcomas. Vet Clin N.Amer.Small Anim. 2001;31:525.

O'Sullivan B, Davis AM, Turcotte R, et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomized trial. Lancet 2002;359:2235-2241.

Poirier VJ, Thamm DH, Kurzman ID, et al. Liposome-encapsulated doxorubicin (Doxil) and doxorubicin in the treatment of vaccine-associated sarcoma in cats. J Vet Intern Med 2002;16:726-731.

Ray-Coquard I, Ranchere-Vince D, Thiesse P, et al. Evaluation of core needle biopsy as a substitute to open biopsy in the diagnosis of soft-tissue masses. Eur J Cancer 2003;39:2021-2025.

Richards JR, Rodan I, Elston T, et al. 2000 Report of the American Association of Feline Practitioners and Academy of Feline Medicine Advisory Panel on Feline Vaccines. Available at: www.aafponline.org/pdf/guidelines_vaccine.pdf. Accessed Apr 18, 2005.

Rogers K, Walker MA, Barton CL, et al. Post-operative brachytherapy for vaccine-associated sarcoma in cats (abstr). American College of Veterinary Radiology. 2000. Ref Type:Conference Proceeding.

Roko JL, Hardy WD. Feline leukemia virus and other retroviruses. In: Sherding R, ed. The cat: diseases and clinical management. New York: Churchill-Livingston, 1994;263-432.

Rudmann DG, Van Alstine WG, Doddy F, et al. Pulmonary and mediastinal metastases of a vaccination-site sarcoma in a cat. Vet Pathol 1996;33:466-469.

Ruslander DM, Rassnick KM, Simon D, Northrup NC, Kristal O, Chretin JD, McCarthy RJ, Berg RJ, Moore AS. Preoperative and postoperative radiation therapy for soft-tissue sarcomas in 28 cats. Veterinary Cancer Society. 2000. Ref Type:Conference Proceeding.

Sandler, I, Teeger, M, and Best, S. Metastatic Vaccine Associated Fibrosarcoma in a 10-Year-Old Cat. Can.Vet.J. 1997;38:374-374.

Sandler I, Teeger M, Best S. Metastatic vaccine associated fibrosarcoma in a 10-year-old cat. Can Vet J 1997;38:374.

Shacter E, Weitzman SA. Chronic inflammation and cancer. Oncology (Huntingt) 2002;16:217-226, 229; discussion 230-232.

Silingardi P, Klein JL, Mesnil M, et al. Growth suppression of transformed BALB/c 3T3 cells by transforming growth factor beta 1 occurs only in the presence of their normal counterparts. Carcinogenesis 1994;15:1181-1185.

Sinibaldi K, Rosen H, Liu S, et al. Tumors associated with metallic implants in animals. Clin Orthop Relat Res 1976;118:257-266.

Starr RM. Vaccine-Associated Feline Sarcoma Task Force: A new model for problem solving in veterinary medicine. J.Amer.Vet Med.Assn. 1998;213:1428-1429.

Tennant B. Feline injection-site fibrosarcomas: results of a BSAVA survey. Journal of Small Animal Practice. 2000;41:181-182.

Turner FC. Sarcomas at sites of subcutaneously implanted Bakelite disks in rats. J Natl Cancer Inst 1941;2:81-83.

Vascellari M, Melchiotti E, Bozza MA, et al. Fibrosarcomas at presumed sites of injection in dogs: characteristics and comparison with non-vaccination site fibrosarcomas and feline post-vaccinal fibrosarcomas. J Vet Med A Physiol Pathol Clin Med 2003;50:286-291.

Williams LE, Banerji N, Klausner JS, Kapur V, Kanjilal S. Establishment of two vaccine-associated feline sarcoma cell lines and determination of in vitro chemosensitivity to doxorubicin and mitoxantrone. Amer.J Vet Res. 2001;62:1354-1357.

Wood CA, Kanjilal S, Kapur V, Fifer-Jezierski A. Surgical treatment of vaccine-associated feline sarcomas. Proceedings VCS 19th Annual Conference. 1999;72. Ref Type:Conference Proceeding

Zagars GK, Ballo MT, Pisters PWT, et al. Preoperative versus postoperative radiation therapy for soft tissue sarcoma: a retrospective comparative evaluation of disease outcome. Int J Radiat Oncol Biol Phys 2003;56:482-488.

Zeiss CJ, Johnson EM, Dubielzig RR. Feline intraocular tumors may arise from transformation of lens epithelium. Vet Pathol 2003;40:355-362.


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