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Journal
 
Factors to consider when evaluating original studies
 

Overview

Importance

  • Is the purpose of the study clear and is the objective of the study relevant?
  • Are there sufficient new and important findings to warrant publication?
  • Has any or all of the information in the manuscript been published previously?

Experimental methods

  • Are experimental methods appropriate for the study?

Interpretation

  • Do the data support the conclusions?

Presentation

  • Is the writing clear, concise, and readable?
  • Should any sections of the manuscript be expanded, condensed, or eliminated?
  • Have authors used abbreviations or jargon to excess?

Specific Manuscript Sections

Title

  • Is the title a clear, accurate representation of the article's content?

Abstract

  • Is the abstract a clear, concise (< 250 words), accurate representation of the major findings of the study?

Introduction

  • Is the introduction focused on relevant aspects of the topic and not just a literature review?
  • Is the reason for performing the study clearly stated?

Materials and Methods

  • Is the study design valid and are experimental methods appropriate?
  • Are experimental methods described in sufficient detail?
  • Are methods for selecting test and control subjects appropriate?
  • Were animals treated humanely?
  • Do authors address potential confounders and biases in subject selection?
  • Are statistical methods valid?

Results

  • Are data presented in a clear and understandable manner?
  • Do authors account for all animals?
  • Are the results credible?
  • Are calculations correct (please scan and spot check)?
  • Do tables, text, and figures agree with and complement each other?
  • Are all tables and figures necessary or is there repetition of material?
  • Is the figure quality adequate?

Discussion

  • Are any results mentioned for the first time in the discussion?
  • Do the authors interpret the data rather than simply restating the results?
  • Are strengths and weaknesses of the methods used acknowledged?
  • Are any ideas or conclusions over- or underemphasized?
  • Do the authors provide a balanced view of the importance of the results?
  • Do the authors cite relevant work of others?
  • Are all conclusions supported by the results?
  • Are any key issues not addressed?
  • Is all of the discussion relevant?
  • Do the authors make any recommendations not supported by their data or beyond the scope of the study?

References

  • Are citations and quotations correct (please scan and spot check)?
  • Are all references pertinent or are some inconsequential?
  • Have any important references been omitted (please provide citations)?

Factors to consider when reviewing manuscripts

  1. Original Study
  2. Retrospective Study
  3. Clinical Report
  4. Descriptive Report
  5. What Is Your Diagnosis?

Version: April 9, 2003

 

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