The AVMA supports the research and development of safe and efficacious drugs, vaccines, chemical compounds, and medical devices that benefit humans and animals through humane and responsible safety testing, using scientifically valid principles and procedures.

The AVMA supports research, development, and validation of alternative testing methods that replace animals, reduce the numbers of animals used, and/or refine animal use to minimize pain and/or distress. The AVMA endorses the activities of the Interagency Coordinating Committee on the Validation of Alternative Methods (established by Public Law 106-545), which are designed to evaluate the scientific validity of new alternative test methods. However, the AVMA will continue to oppose legislation that seeks to eliminate animal-based safety assessment unless that legislation is based on sound scientific principles.