The AVMA supports the research and development of safe and efficacious drugs, vaccines, chemical compounds, and medical devices that benefit humans and animals through humane and responsible safety testing, using scientifically valid principles and procedures.

The AVMA supports research, development, and validation of alternative testing methods that replace animals, reduce the numbers of animals used, and/or refine animal use to minimize pain and/or distress. The AVMA endorses activities that are designed to evaluate the scientific validity of new alternative test methods. However, the AVMA supports the protection of human and animal health and will continue to oppose activities that seek to eliminate animal-based safety assessments that are not based on sound scientific principles.